Genome Size: Does Bigger Mean Worse?
نویسندگان
چکیده
Genome sizes vary enormously. This variation in DNA content correlates with effective population size, suggesting that deleterious additions to the genome can accumulate in small populations. On this view, the increased complexity of biological functions associated with large genomes partly reflects evolutionary degeneration.
منابع مشابه
Scale models
Scientists have long noted the link between small genome size and high metabolic rates. Bats and birds have the smallest genomes of vertebrates, and flightless birds tend to have bigger genomes than fliers. The genome is typically present in every cell so carrying around a smaller genome suggests you can have smaller cells, researchers have speculated. Smaller cells mean a larger surface-to-vol...
متن کاملReassessment of the Genome Size in Elaeis guineensis and Elaeis oleifera, and Its Interspecific Hybrid
Aiming at generating a comprehensive genomic database on Elaeis spp., our group is leading several R&D initiatives with Elaeis guineensis (African oil palm) and Elaeis oleifera (American oil palm), including the whole-genome sequencing of the last. Genome size estimates currently available for this genus are controversial, as they indicate that American oil palm genome is about half the size of...
متن کاملEgg-size evolution in aquatic environments: does oxygen availability constrain size?
Selection against large eggs has been proposed for aquatic environments, putatively because large eggs should have more difficulty obtaining the required oxygen. Here, we use brown trout (Salmo trutta) eggs to provide an experimental test of this hypothesis. At high levels of dissolved oxygen (14 mg l(-1)), egg survival was high and independent of egg size. At low oxygen levels (2.3 mg l(-1)), ...
متن کاملStatistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies
Genome-wide association studies (GWAS) have identified hundreds of SNPs responsible for variation in human quantitative traits. However, genome-wide-significant associations often fail to replicate across independent cohorts, in apparent inconsistency with their apparent strong effects in discovery cohorts. This limited success of replication raises pervasive questions about the utility of the ...
متن کاملWhen bigger is not better: selection against large size, high condition and fast growth in juvenile lemon sharks.
Selection acting on large marine vertebrates may be qualitatively different from that acting on terrestrial or freshwater organisms, but logistical constraints have thus far precluded selection estimates for the former. We overcame these constraints by exhaustively sampling and repeatedly recapturing individuals in six cohorts of juvenile lemon sharks (450 age-0 and 255 age-1 fish) at an enclos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 14 شماره
صفحات -
تاریخ انتشار 2004